Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656150 | 0.85 | ADORA2A (0.57) | ADORA2AADORA1 | |
| SCHEMBL5095982 | 0.80 | ADORA2A (0.47) | ADORA2A | |
| SCHEMBL5096071 | 0.76 | — | — | |
| SCHEMBL5410869 | 0.73 | ADORA2A (0.62) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL6010317 | 0.70 | ADORA2A (0.43) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL6010026 | 0.70 | ADORA2A (0.45) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL5103136 | 0.69 | ADORA2A (0.63) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL5651588 | 0.69 | ADORA2A (0.56) | ADORA2AADORA1 | |
| SCHEMBL6009718 | 0.68 | — | — | |
| SCHEMBL3542516 | 0.67 | ADORA2A (0.60) | ADORA3ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070932-A1 | Triazolo[ 1,5-A] Pyrimidines And Pyrazolo[ 1,5-A] Pyrimidines And Methods Of Making And Using The Same | BIOGEN IDEC MA INC. | 2008-03-20 | — | — | US | disclosed |
| EP-1618108-A2 | TRIAZOLO[1,5-A]PYRIMIDINES AND PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS A2A ADENOSINE RECEPTOR ANTAGONISTS | Biogen Idec MA Inc. (US) | 2006-01-25 | — | — | EP | disclosed |
| WO-2004092171-A2 | TRIAZOLO[1,5-A]PYRIMIDINES AND PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS A2A ADENOSIN E RECEPTOR ANTAGONISTS | BIOGEN IDEC MA INC. (US) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070932-A1 | Triazolo[ 1,5-A] Pyrimidines And Pyrazolo[ 1,5-A] Pyrimidines And Methods Of Making And Using The Same | ADORA2B, ADORA2A, ADORA1 | ADORA3 4/4885ADORA2B 1/4885ADORA2A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.