Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 11/20 | 0.59 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28604564 | 0.98 | SCN10A (0.58) | SCN10ANPBWR1AAK1KDM4EKIF11 | |
| Bromide SCHEMBL28604567 | 0.98 | SCN10A (0.58) | SCN10ANPBWR1AAK1KDM4EKIF11 | |
| Bromide SCHEMBL31276057 | 0.98 | SCN10A (0.58) | SCN10ANPBWR1AAK1KDM4EKIF11 | |
| SCHEMBL5681322 | 0.88 | SCN10A (0.75) | SCN10ANPBWR1AAK1IDO1 | |
| SCHEMBL12410866 | 0.88 | SCN10A (0.55) | SCN10ANPBWR1KDM4EKIF11LMNA | |
| SCHEMBL15311094 | 0.86 | SCN10A (0.58) | SCN10AKDM4EKIF11LMNAHSD17B10 | |
| SCHEMBL15311092 | 0.86 | SCN10A (0.58) | SCN10AKDM4EKIF11LMNAHSD17B10 | |
| SCHEMBL5682994 | 0.85 | SCN10A (0.59) | SCN10ANPBWR1KDM4EKIF11LMNA | |
| SCHEMBL15172700 | 0.81 | SCN10A (0.46) | SCN10AKDM4ELMNAHSD17B10TAAR1 | |
| SCHEMBL15172719 | 0.81 | SCN10A (0.46) | SCN10AKDM4ELMNAHSD17B10TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132496-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-06-05 | — | — | US | disclosed |
| US-7326791-B2 | Carboxylic acid amides, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO., KG (DE) | 2008-02-05 | — | — | US | disclosed |
| US-20040220169-A1 | Carboxylic acid amides, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132496-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | F12, F11, F2 | SCN10A 1465/4885NPBWR1 4242/4885AAK1 3313/4885 |
| US-20040220169-A1 | Carboxylic acid amides, the preparation thereof, and their use as pharmaceutical compositions | F12, F11, F2 | SCN10A 1505/4885NPBWR1 3932/4885AAK1 2401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.