Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723173 | 0.90 | HPGD (0.64) | HPGDPPARGHDAC8MMP3PLK1 | |
| SCHEMBL20734835 | 0.89 | HPGD (0.66) | HPGDPPARGHDAC8MMP3PLK1 | |
| SCHEMBL4722989 | 0.87 | KDM4E (0.50) | HPGDPPARGHDAC1HDAC6ALDH1A1 | |
| SCHEMBL3643350 | 0.86 | HPGD (0.62) | HPGDPPARGHDAC8MMP3PLK1 | |
| SCHEMBL17514068 | 0.84 | HPGD (0.61) | HPGDPPARGHDAC8MMP3PLK1 | |
| SCHEMBL30301313 | 0.84 | TSHR (0.73) | HPGDPPARGHDAC8MMP3PLK1 | |
| SCHEMBL1093718 | 0.84 | TSHR (0.73) | HPGDPPARGHDAC8MMP3PLK1 | |
| SCHEMBL4721719 | 0.83 | HDAC8 (0.62) | HPGDPPARGHDAC8MMP3PLK1 | |
| SCHEMBL9831671 | 0.83 | PPARG (0.82) | HPGDPPARGHDAC8MMP3PLK1 | |
| SCHEMBL14058606 | 0.83 | TSHR (0.66) | HPGDPPARGHDAC8MMP3PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176857-A1 | 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFIZER INC. | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176857-A1 | 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors | TBXA2R, P2RY4, PF4 | HPGD 800/4885PPARG 1458/4885HDAC8 3029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.