Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 19/20 | 0.63 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596893 | 0.78 | PRKCB (0.86) | PRKCB | |
| SCHEMBL596914 | 0.78 | PRKCB (1.00) | PRKCB | |
| SCHEMBL597658 | 0.77 | PRKCB (1.00) | PRKCB | |
| SCHEMBL3457844 | 0.77 | CCNA2 (0.62) | PRKCBCCNA2CDK2CCNA1 | |
| SCHEMBL598986 | 0.77 | PRKCB (1.00) | PRKCB | |
| SCHEMBL597116 | 0.77 | PRKCB (1.00) | PRKCB | |
| SCHEMBL601757 | 0.77 | PRKCB (1.00) | PRKCB | |
| SCHEMBL598342 | 0.77 | PRKCB (1.00) | PRKCB | |
| SCHEMBL596951 | 0.77 | PRKCB (1.00) | PRKCB | |
| SCHEMBL597024 | 0.76 | PRKCB (1.00) | PRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407971-B2 | Substituted pyrrolo-pyrazole derivatives as kinase inhibitors | PFIZER ITALIA S.R.L. (IT) | 2008-08-05 | — | — | US | claimed |