Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5107023 | 0.86 | IDH2 (0.45) | KMT2AMEN1IDH2ATMALDH1A1 | |
| SCHEMBL5111796 | 0.84 | AKR1C3 (0.42) | AKR1C3AKR1C2KMT2AMEN1HPGD | |
| Trifluoroacetic Acid SCHEMBL5112036 | 0.83 | IDH2 (0.45) | KMT2AMEN1IDH2RAB9ACNR1 | |
| SCHEMBL16438568 | 0.83 | KMT2A (0.53) | AKR1C3AKR1C2KMT2AMEN1HPGD | |
| Trifluoroacetic Acid SCHEMBL5099366 | 0.81 | CNR1 (0.45) | AKR1C3AKR1C2KMT2AMEN1LMNA | |
| SCHEMBL5106389 | 0.80 | KDM4E (0.53) | AKR1C3AKR1C2KMT2AMEN1LMNA | |
| Trifluoroacetic Acid SCHEMBL5103314 | 0.79 | IDH2 (0.44) | KMT2AMEN1IDH2RAB9ACNR1 | |
| Trifluoroacetic Acid SCHEMBL5106872 | 0.79 | MEN1 (0.44) | KMT2AMEN1SMN1; SMN2ATMRAB9A | |
| SCHEMBL5106415 | 0.79 | MAPT (0.51) | AKR1C3AKR1C2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5106950 | 0.76 | CNR1 (0.48) | KMT2AMEN1IDH2FADS1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | AKR1C3 1908/4885AKR1C2 2538/4885KMT2A 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.