Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 4/20 | 0.44 |
| ▸ | IDH2 | P48735 | 5/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5107023 | 0.90 | IDH2 (0.45) | IDH2SHMT1MEN1KMT2ATDP1 | |
| Trifluoroacetic Acid SCHEMBL5099269 | 0.90 | AKR1C3 (0.44) | CNR1IDH2AKR1C3AKR1C2CNR2 | |
| Trifluoroacetic Acid SCHEMBL5103314 | 0.88 | IDH2 (0.44) | CNR1FABP4IDH2FABP5SHMT1 | |
| Trifluoroacetic Acid SCHEMBL5107022 | 0.86 | AKR1C3 (0.44) | IDH2AKR1C3AKR1C2CNR2MEN1 | |
| Trifluoroacetic Acid SCHEMBL5113233 | 0.86 | FABP4 (0.46) | FABP4IDH2FABP5SHMT1AKR1C3 | |
| SCHEMBL5099368 | 0.84 | CNR1 (0.43) | CNR1FABP4IDH2FABP5MEN1 | |
| Trifluoroacetic Acid SCHEMBL5103915 | 0.82 | FABP4 (0.44) | FABP4IDH2FABP5SHMT1AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL5112036 | 0.82 | IDH2 (0.45) | CNR1FABP4IDH2FABP5SHMT1 | |
| Trifluoroacetic Acid SCHEMBL5106872 | 0.82 | MEN1 (0.44) | MEN1TP53KMT2AL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5103795 | 0.82 | CHRM3 (0.42) | AKR1C3AKR1C2CNR2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | CNR1 98/4885FABP4 4255/4885IDH2 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.