Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 6/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111968 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTNR2F2HTTL3MBTL1 | |
| SCHEMBL962598 | 0.90 | PTGER3 (0.41) | SMN1; SMN2MAPTNR2F2HTTPHGDH | |
| SCHEMBL962596 | 0.90 | PTGER3 (0.41) | SMN1; SMN2MAPTNR2F2HTTPHGDH | |
| SCHEMBL964365 | 0.89 | PTGER3 (0.44) | SMN1; SMN2MAPTNR2F2HTTPTGER3 | |
| SCHEMBL964366 | 0.89 | PTGER3 (0.44) | SMN1; SMN2MAPTNR2F2HTTPTGER3 | |
| SCHEMBL5126172 | 0.89 | HDAC1 (0.37) | SMN1; SMN2MAPTNR2F2HTTHDAC1 | |
| SCHEMBL5126177 | 0.89 | HDAC1 (0.37) | SMN1; SMN2MAPTNR2F2HTTHDAC1 | |
| SCHEMBL963423 | 0.88 | FLT1 (0.41) | SMN1; SMN2MAPTNR2F2HTTPHGDH | |
| SCHEMBL965317 | 0.88 | PTGER3 (0.40) | SMN1; SMN2MAPTNR2F2HTTPHGDH | |
| SCHEMBL965506 | 0.88 | MAPT (0.39) | SMN1; SMN2MAPTNR2F2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194617-A1 | Fused ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194617-A1 | Fused ring compound | SLC5A1, SLC5A2, GPR119 | SMN1; SMN2 3745/4885MAPT 4343/4885NR2F2 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.