Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4691747 | 0.95 | PDE10A (0.37) | PDE10AL3MBTL1FPR3FPR2ADRA1D | |
| SCHEMBL4690301 | 0.92 | TSHR (0.38) | PDE10AL3MBTL1FPR3FPR2DRD2 | |
| SCHEMBL4686652 | 0.91 | PDE10A (0.38) | PDE10AL3MBTL1FPR3FPR2DRD2 | |
| SCHEMBL4687447 | 0.91 | PDE10A (0.39) | PDE10AL3MBTL1FPR3FPR2ADRA1D | |
| SCHEMBL4691347 | 0.91 | TSHR (0.39) | PDE10AL3MBTL1FPR3FPR2DRD2 | |
| SCHEMBL4686983 | 0.90 | PDE10A (0.41) | PDE10AL3MBTL1DRD2HTR2ADRD3 | |
| SCHEMBL1847387 | 0.90 | PDE10A (0.40) | PDE10AL3MBTL1DRD2HTR2ADRD3 | |
| SCHEMBL4688414 | 0.88 | L3MBTL1 (0.37) | L3MBTL1ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL4686584 | 0.88 | PDE10A (0.34) | PDE10AL3MBTL1DRD2HTR2ADRD3 | |
| SCHEMBL4690005 | 0.86 | PDE10A (0.40) | PDE10AL3MBTL1FPR3FPR2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375115-B2 | 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2008-05-20 | — | — | US | disclosed |