Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930441 | 0.98 | OPRM1 (0.41) | OPRM1OPRD1OPRK1CACNA2D1CHRM2 | |
| SCHEMBL4691751 | 0.95 | OPRM1 (0.43) | OPRM1OPRD1OPRK1CACNA2D1CHRM2 | |
| SCHEMBL4690302 | 0.92 | OPRM1 (0.39) | OPRM1OPRD1OPRK1CACNA2D1CHRM2 | |
| SCHEMBL4691349 | 0.91 | OPRM1 (0.39) | OPRM1OPRD1OPRK1CACNA2D1CHRM2 | |
| SCHEMBL4686658 | 0.91 | OPRM1 (0.44) | OPRM1OPRD1OPRK1CACNA2D1CHRM2 | |
| SCHEMBL4687449 | 0.90 | OPRM1 (0.47) | OPRM1OPRD1OPRK1CACNA2D1CHRM2 | |
| SCHEMBL4686988 | 0.89 | OPRM1 (0.49) | OPRM1OPRD1OPRK1CACNA2D1CHRM2 | |
| SCHEMBL4688418 | 0.89 | OPRM1 (0.49) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL4686586 | 0.89 | OPRM1 (0.39) | OPRM1OPRD1OPRK1CACNA2D1CHRM2 | |
| SCHEMBL1847389 | 0.89 | OPRM1 (0.48) | OPRM1OPRD1OPRK1CACNA2D1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375115-B2 | 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2008-05-20 | — | — | US | disclosed |