Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31002670 | 0.81 | MEN1 (0.68) | MEN1KMT2AGAAALDH1A1TDP1 | |
| SCHEMBL1118619 | 0.81 | MEN1 (0.68) | MEN1KMT2AGAAALDH1A1TDP1 | |
| SCHEMBL2478920 | 0.81 | MEN1 (0.48) | MEN1KMT2AGAAALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL1408626 | 0.79 | MEN1 (0.47) | MEN1KMT2AGAAALDH1A1NPC1 | |
| SCHEMBL22968438 | 0.79 | MEN1 (0.47) | MEN1KMT2AGAAALDH1A1NPC1 | |
| SCHEMBL15806544 | 0.79 | DEPTOR (0.47) | MEN1KMT2AGAAALDH1A1NPC1 | |
| SCHEMBL5360716 | 0.79 | RAPGEF4 (0.48) | MEN1KMT2AGAAALDH1A1NPC1 | |
| Phenylhydrazine SCHEMBL19642856 | 0.77 | IDO1 (0.61) | MEN1KMT2AGAATDP1NPC1 | |
| Hydrochloric Acid SCHEMBL1807762 | 0.77 | RAPGEF4 (0.47) | MEN1KMT2AGAAALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL28009377 | 0.77 | DEPTOR (0.46) | MEN1KMT2AGAAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | PNPO, DPYD, PNP | MEN1 2912/4885KMT2A 4285/4885GAA 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.