Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.94 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL2732791 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL5966797 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL17627567 | 0.97 | CA4 (0.90) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL27448234 | 0.97 | CA4 (0.90) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL27751115 | 0.97 | CA4 (0.90) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL276988 | 0.97 | CA4 (1.00) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL2235356 | 0.97 | CA4 (1.00) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL3657 | 0.97 | CA4 (1.00) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL11060179 | 0.97 | CA4 (1.00) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL715802 | 0.97 | CA4 (1.00) | CA4CASP1FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121577599-A | Microplastic fluorescence detection method based on carbon quantum dots | 大连理工大学 | 2026-02-27 | — | — | CN | claimed |
| US-12517058-B2 | Indicator rapidly responding to subtle pH change | SUZHOU TURING MICROBIAL TECHNOLOGY CO., LTD. (CN) | 2026-01-06 | — | — | US | claimed |
| CN-119776000-A | Preparation and application of hydrogen sulfide response aggregation type gold nano probe | 福州大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119161974-A | Method, device and application for photo-thermal amplification and rapid detection of multiple genes | 江南大学 | 2024-12-20 | — | — | CN | claimed |
| US-20240201092-A1 | INDICATOR RAPIDLY RESPONDING TO SUBTLE PH CHANGE | SUZHOU TURING MICROBIAL TECHNOLOGY CO., LTD. (CN) | 2024-06-20 | — | — | US | claimed |
| CN-117695244-A | Anti-tumor nano preparation and application thereof in preparation of breast cancer therapeutic drugs | 江西中医药大学 | 2024-03-15 | — | — | CN | claimed |
| CN-117571781-A | Method for detecting fluorine content in lithium battery material | 泾河新城陕煤技术研究院新能源材料有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-115786454-A | Nucleic acid sample preservation reagent and application thereof | 杭州安旭生物科技股份有限公司 | 2023-03-14 | — | — | CN | claimed |
| WO-2023029251-A1 | RAPID-RESPONSE SLIGHT PH CHANGE INDICATOR | 苏州图灵微生物科技有限公司 | 2023-03-09 | — | — | WO | claimed |
| CN-111562243-B | Metallothionein detection method based on carbon quantum dot-gold nanoparticle system | 太原理工大学 | 2022-02-22 | — | — | CN | claimed |
| CN-101201318-B | Detection of trace amount gold nanometer particle by HAuCl4 spectrophotometric method | UNIV GUANGXI NORMAL | 2010-09-01 | — | — | CN | claimed |
| CN-101201318-A | Detection of trace amount gold nanometer particle by HAuCl4 spectrophotometric method | UNIV GUANGXI NORMAL (CN) | 2008-06-18 | — | — | CN | claimed |
| US-20070269478-A1 | METHOD OF PREPARING ACELLULARIZED, BIOCOMPATIBLE, IMPLANTABLE MATERIAL | TECNOBIOMEDICA S.P.A. (IT) | 2007-11-22 | — | — | US | claimed |
| US-20050260727-A1 | Crystal structure of the mitochondrial protoporphyrinogen IX oxidase | BAYER CROPSCIENCE AG (DE) | 2005-11-24 | — | — | US | claimed |
| CN-1150888-C | Peroral active agent suspension | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-05-26 | — | — | CN | claimed |
| EP-0795337-B1 | A method of preparing biological implantation material | SORIN BIOMEDICA CARDIO SPA (IT) | 2002-12-04 | — | — | EP | claimed |
| CN-1295462-A | Peroral active agent suspension | BOEHRINGER INGEHEIM PHARMA KG (DE) | 2001-05-16 | — | — | CN | claimed |
| EP-0795337-A2 | A method of preparing biological implantation material | SORIN BIOMEDICA CARDIO S.p.A. (IT) | 1997-09-17 | — | — | EP | claimed |
| US-5352452-A | Anticoagulants, enzyme activity | BOEHRINGER MANNHEIM GMBH (DE) | 1994-10-04 | — | — | US | claimed |
| US-5188834-A | Fixing with aldehyde, treating with aminodicarboxylic acid in buffered acidic solution to bind excess aldehyde | SORIN BIOMEDICA S.P.A. (IT) | 1993-02-23 | — | — | US | claimed |