Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16893446 | 0.73 | MAPT (0.57) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL15545929 | 0.72 | MEN1 (0.63) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL3052808 | 0.72 | BRD4 (0.39) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL3056704 | 0.71 | BRD4 (0.38) | SUCNR1CNR2 | |
| SCHEMBL3058707 | 0.71 | MAPT (0.40) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL3058715 | 0.71 | KMT2A (0.55) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL16904651 | 0.71 | MAPT (0.68) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL16893399 | 0.71 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL3042819 | 0.69 | KMT2A (0.44) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL29281561 | 0.69 | KDM4E (0.49) | KMT2AMAPTALDH1A1HDAC1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008051197-A2 | SMALL-MOLECULE BOTULINUM TOXIN INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-05-02 | — | — | WO | disclosed |