SCHEMBL5114437

SCHEMBL5114437

c1ccc(-c2cccc(CCc3cccc(-c4ccccc4)n3)n2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
RAB9A P51151 1/20 0.65
PDE10A Q9Y233 6/20 0.56
KCNH2 Q12809 1/20 0.56
ASIC3 Q9UHC3 2/20 0.54
TRPV3 Q8NET8 1/20 0.49
HTR1A P08908 1/20 0.42
DRD2 P14416 1/20 0.42
HTR2A P28223 1/20 0.42
HTR7 P34969 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ADORA2A P29274 2/20 0.41
AURKA O14965 1/20 0.41
HSP90AA1 P07900 1/20 0.41
PRKACA P17612 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31705085 0.88 RAB9A (0.56) MEN1KMT2ARAB9APDE10AKCNH2
SCHEMBL27651070 0.88 MEN1 (0.56) MEN1KMT2ARAB9APDE10AKCNH2
SCHEMBL12576617 0.88 RAB9A (0.56) MEN1KMT2ARAB9APDE10AKCNH2
SCHEMBL5645917 0.86 MEN1 (0.65) MEN1KMT2ARAB9APDE10AKCNH2
SCHEMBL28067777 0.86 PDE10A (0.49) MEN1KMT2ARAB9APDE10AKCNH2
SCHEMBL31249572 0.85 KCNH2 (0.56) MEN1KMT2ARAB9APDE10AKCNH2
SCHEMBL17261488 0.83 MEN1 (0.50) MEN1KMT2ARAB9APDE10AASIC3
SCHEMBL3854280 0.83 MEN1 (0.50) MEN1KMT2ARAB9APDE10AKCNH2
SCHEMBL7453825 0.83 PDE10A (0.66) MEN1KMT2ARAB9APDE10AKCNH2
SCHEMBL2953474 0.83 MEN1 (0.60) MEN1KMT2ARAB9APDE10AASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
EP-1683804-A2 PLATINUM COMPLEX AND LUMINESCENT ELEMENT Takasago International Corporation (JP) 2006-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070103060-A1 Platinum complex and light emitting device UBE2D3, PCID2, CCND2 MEN1 1473/4885KMT2A 1827/4885RAB9A 1399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.