Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29944152 | 0.87 | CA2 (0.57) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL28409555 | 0.85 | CA2 (0.55) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL3057081 | 0.85 | CYP1A2 (0.57) | CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL74008 | 0.84 | CA2 (0.63) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL27545972 | 0.84 | KMT2A (0.50) | ALDH1A1CYP1A2CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL16114691 | 0.84 | MAPT (0.49) | KDM4EALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL15569845 | 0.84 | CA2 (0.53) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL5114730 | 0.82 | CA2 (0.61) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL6791052 | 0.81 | ATM (0.58) | CA2CYP19A1ATMKDM4EPOLB | |
| SCHEMBL11552660 | 0.81 | CA2 (0.55) | CA2CYP19A1ATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096942-A1 | Substituted Hydroxyethylamines | ELAN PHARMACEUTICALS, INC. | 2008-04-24 | — | — | US | disclosed |
| US-7312360-B2 | Substituted hydroxyethylamines | ELAN PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-20040044072-A1 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096942-A1 | Substituted Hydroxyethylamines | BACE1, BACE2, MME | CA2 3235/4885CYP19A1 673/4885ATM 3280/4885 |
| US-20040044072-A1 | Substituted hydroxyethylamines | BACE1, BACE2, PSEN1 | CA2 3191/4885CYP19A1 421/4885ATM 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.