SCHEMBL5115147

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5116820	0.89	BRD4 (0.54)	ADRA1BTOP2ABACE1BACE2BRD4
	SCHEMBL5114519	0.89	ADRA1B (0.60)	ADRA1BTOP2ABACE1BACE2BRD4
	SCHEMBL5130378	0.88	BACE1 (0.55)	ADRA1BTOP2ABACE1BACE2BRD4
	SCHEMBL5117981	0.86	MAPT (0.61)	ADRA1BTOP2ABACE1BRD4
	SCHEMBL5129215	0.85	ADRA1B (0.45)	ADRA1BTOP2ABACE1BACE2BRD4
	SCHEMBL5124542	0.85	ADRA1B (0.63)	ADRA1BTOP2ABACE1BACE2BRD4
	SCHEMBL25416714	0.82	ADRA1B (0.91)	ADRA1BTOP2ABACE1BACE2BRD4
	SCHEMBL5122888	0.81	ADRA1B (0.52)	ADRA1BTOP2ABACE1BACE2BRD4
	SCHEMBL5118052	0.81	ADRA1B (0.52)	ADRA1BTOP2ABACE1BACE2BRD4
	SCHEMBL5118071	0.81	ADRA1B (0.51)	ADRA1BTOP2ABACE1BACE2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.