SCHEMBL5115791

SCHEMBL5115791

C/C(CC(C)(C)O)=N\O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5115794 1.00
SCHEMBL13298275 0.79
SCHEMBL164190 0.79
SCHEMBL164191 0.79
SCHEMBL1168602 0.74
SCHEMBL13661558 0.74
SCHEMBL1168598 0.74
SCHEMBL14751235 0.71
SCHEMBL11867885 0.71
SCHEMBL12757036 0.70 MAPT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2227466-B1 HETEROARYL-SUBSTITUTED PIPERIDINES BAYER SCHERING PHARMA AG (DE) 2011-04-20 EP disclosed
US-7449581-B2 6-Substituted pyrido-pyrimidines POCHE PALO ALTO LLC (US) 2008-11-11 US disclosed
US-7449581-B2 6-Substituted pyrido-pyrimidines POCHE PALO ALTO LLC (US) 2008-11-11 US disclosed
US-7449581-B2 6-Substituted pyrido-pyrimidines POCHE PALO ALTO LLC (US) 2008-11-11 US disclosed
US-20070135458-A1 6-Substituted pyrido-pyrimidines CHEN JIAN J 2007-06-14 US disclosed
US-20070135458-A1 6-Substituted pyrido-pyrimidines CHEN JIAN J 2007-06-14 US disclosed
US-20070135458-A1 6-Substituted pyrido-pyrimidines CHEN JIAN J 2007-06-14 US disclosed
US-7169794-B2 6-substituted pyrido-pyrimidines ROCHE PALO ALTO LLC (US) 2007-01-30 US disclosed
US-7169794-B2 6-substituted pyrido-pyrimidines ROCHE PALO ALTO LLC (US) 2007-01-30 US disclosed
US-7169794-B2 6-substituted pyrido-pyrimidines ROCHE PALO ALTO LLC (US) 2007-01-30 US disclosed
EP-1301470-A1 DEGRADABLE CROSSLINKERS, COMPOSITIONS THEREFROM, AND METHODS OF THEIR PREPARATION AND USE 3M Innovative Properties Company (US) 2003-04-16 EP disclosed
WO-2002004408-A1 DEGRADABLE CROSSLINKERS, COMPOSITIONS THEREFROM, AND METHODS OF THEIR PREPARATION AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO disclosed
WO-2002004548-A1 POLYMER COMPOSITIONS WITH ENERGETICALLY DEGRADABLE CROSSLINKER 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO disclosed
US-4335234-A AROMATIC HYDROCARBON AND WATER-IMMISCIBLE ALKANOL; PREPARATION OF POLYPHENYLENE ETHERS GENERAL ELECTRIC COMPANY (US) 1982-06-15 US disclosed
US-4287321-A PREPARED IN THE PRESENCE OF A MANGANESE CHELATE COMPOUND GENERAL ELECTRIC COMPANY (US) 1981-09-01 US disclosed
US-4207406-A MANGANESE CHELATE CATALYST GENERAL ELECTRIC COMPANY (US) 1980-06-10 US disclosed
US-4102865-A Moderation of manganese chelate catalyzed polymerization of phenolic monomers with polyfunctional alkanolamines GENERAL ELECTRIC COMPANY (US) 1978-07-25 US disclosed
US-4097462-A OXIDATIVE COUPLING OF A PHENOL, PRECIPITATION, MANGANESE (II) HYDROXYOXIME CHELATE CATALYST GENERAL ELECTRIC COMPANY (US) 1978-06-27 US disclosed
US-4075174-A BIS-SECONDARY DIAMINES GENERAL ELECTRIC COMPANY (US) 1978-02-21 US disclosed
US-3956242-A Preparation of polyphenylene oxide using a manganese (II) ω-hydroxyoxime chelate reaction promoter GENERAL ELECTRIC COMPANY (US) 1976-05-11 US disclosed