⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115791 | 1.00 | — | — | |
| SCHEMBL13298275 | 0.79 | — | — | |
| SCHEMBL164190 | 0.79 | — | — | |
| SCHEMBL164191 | 0.79 | — | — | |
| SCHEMBL1168602 | 0.74 | — | — | |
| SCHEMBL13661558 | 0.74 | — | — | |
| SCHEMBL1168598 | 0.74 | — | — | |
| SCHEMBL14751235 | 0.71 | — | — | |
| SCHEMBL11867885 | 0.71 | — | — | |
| SCHEMBL12757036 | 0.70 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449581-B2 | 6-Substituted pyrido-pyrimidines | POCHE PALO ALTO LLC (US) | 2008-11-11 | — | — | US | disclosed |
| US-20070135458-A1 | 6-Substituted pyrido-pyrimidines | CHEN JIAN J | 2007-06-14 | — | — | US | disclosed |
| US-7169794-B2 | 6-substituted pyrido-pyrimidines | ROCHE PALO ALTO LLC (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1361880-B1 | 6-SUBSTITUTED PYRIDO-PYRIMIDINES | HOFFMANN LA ROCHE (CH) | 2005-09-28 | — | — | EP | disclosed |
| US-20040116698-A1 | 6-Substituted pyrido-pyrimidines | CHEN JIAN JEFFREY (US) | 2004-06-17 | — | — | US | disclosed |
| US-6696566-B2 | SELECTIVE P38 KINASE INHIBITORS RELATIVE TO CYCLIN-DEPENDENT KINASES AND TYROSINE KINASES | SYNTEX (U.S.A.) LLC | 2004-02-24 | — | — | US | disclosed |
| US-6652970-B1 | Stable after transformation | 3M INNOVATIVE PROPERTIES COMPANY | 2003-11-25 | — | — | US | disclosed |
| US-20030171584-A1 | Treating p38 mediated disorders such as arthritis, Crohns disease, irritable bowel syndrome adult respiratory distress syndrome or chronic obstructive pulmonary disease. | SYNTEX (U.S.A.) LLC | 2003-09-11 | — | — | US | disclosed |
| EP-1301470-A1 | DEGRADABLE CROSSLINKERS, COMPOSITIONS THEREFROM, AND METHODS OF THEIR PREPARATION AND USE | 3M Innovative Properties Company (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004548-A1 | POLYMER COMPOSITIONS WITH ENERGETICALLY DEGRADABLE CROSSLINKER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |
| US-5250486-A | Catalyst comprising a manganese compound, a chelate compound, a base and an unsaturated ketone or ether; controlled molecular weight; odorless; stabile thermal properties when blended with styrene resins | GENERAL ELECTRIC COMPANY (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0491190-A2 | Polyphenylene ether process and resin composition | GENERAL ELECTRIC COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |
| US-5037943-A | Oxidative coupling using alkaline catalysts system of manganese chelate and unsaturated or diketune or vinyl ether | GENERAL ELECTRIC CO. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4335234-A | AROMATIC HYDROCARBON AND WATER-IMMISCIBLE ALKANOL; PREPARATION OF POLYPHENYLENE ETHERS | GENERAL ELECTRIC COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| US-4287321-A | PREPARED IN THE PRESENCE OF A MANGANESE CHELATE COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1981-09-01 | — | — | US | disclosed |
| US-4207406-A | MANGANESE CHELATE CATALYST | GENERAL ELECTRIC COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
| US-4102865-A | Moderation of manganese chelate catalyzed polymerization of phenolic monomers with polyfunctional alkanolamines | GENERAL ELECTRIC COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4097462-A | OXIDATIVE COUPLING OF A PHENOL, PRECIPITATION, MANGANESE (II) HYDROXYOXIME CHELATE CATALYST | GENERAL ELECTRIC COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4075174-A | BIS-SECONDARY DIAMINES | GENERAL ELECTRIC COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3956242-A | Preparation of polyphenylene oxide using a manganese (II) ω-hydroxyoxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |