SCHEMBL5115799

SCHEMBL5115799

CCCN1C(=O)Cc2cc(N3CC(CNC(=O)CC)OC3=O)ccc21

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.47
MAOB P27338 4/20 0.47
MAOA P21397 3/20 0.47
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
CALML3 P27482 1/20 0.47
SDHA P31040 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5115796 1.00 F10 (0.47) F10MAOBMAOALMNAPTGS1
SCHEMBL5115312 0.93 MAOB (0.48) F10MAOBMAOALMNAPTGS1
SCHEMBL5115314 0.93 MAOB (0.48) F10MAOBMAOALMNAPTGS1
SCHEMBL5116380 0.92 MAOB (0.48) F10MAOBMAOALMNAPTGS1
SCHEMBL5116374 0.92 MAOB (0.48) F10MAOBMAOALMNAPTGS1
SCHEMBL5122630 0.91 MAOA (0.57) F10MAOBMAOALMNAPTGS1
SCHEMBL5122626 0.91 MAOA (0.57) F10MAOBMAOALMNAPTGS1
SCHEMBL5512879 0.90 MAOB (0.47) F10MAOBMAOALMNAPTGS1
SCHEMBL5512875 0.90 MAOB (0.47) F10MAOBMAOALMNAPTGS1
SCHEMBL5112639 0.89 F10 (0.56) F10MAOBMAOALMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents PFIZER INC 2008-10-23 US claimed
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents PFIZER INC 2008-10-23 US disclosed
EP-1781643-A1 OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS Pharmacia & Upjohn Company LLC (US) 2007-05-09 EP disclosed
WO-2006016220-A1 OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents OXA1L, OXSR1, OXER1 F10 784/4885MAOB 412/4885MAOA 447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.