⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82112 | 0.78 | — | — | |
| SCHEMBL5111424 | 0.77 | — | — | |
| SCHEMBL3283077 | 0.73 | ALOX5 (0.45) | — | |
| SCHEMBL1750672 | 0.73 | — | — | |
| SCHEMBL9396873 | 0.73 | — | — | |
| SCHEMBL5118135 | 0.73 | — | — | |
| SCHEMBL9912431 | 0.71 | — | — | |
| SCHEMBL5264334 | 0.71 | — | — | |
| SCHEMBL2159354 | 0.71 | — | — | |
| SCHEMBL2917865 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054669-B9 | USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES | ROCHE DIAGNOSTICS GMBH (DE) | 2004-09-15 | — | — | EP | claimed |
| EP-1054669-B1 | USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES | ROCHE DIAGNOSTICS GMBH (DE) | 2003-07-16 | — | — | EP | claimed |
| EP-1054669-A2 | USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 2000-11-29 | — | — | EP | claimed |
| WO-1999042089-A2 | USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | claimed |
| US-7365067-B2 | Indanol derivative | SANKYO COMPANY, LIMITED (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20070197570-A1 | Indanol derivative | SANKYO COMPANY, LIMITED (JP) | 2007-08-23 | — | — | US | disclosed |
| EP-1746095-A1 | INDANOL DERIVATIVE | Sankyo Company, Limited (JP) | 2007-01-24 | — | — | EP | disclosed |