SCHEMBL5116967

SCHEMBL5116967

Brc1ccccc1Sc1ccccn1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
MAPT P10636 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
USP2 O75604 2/20 0.51
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
EHMT2 Q96KQ7 1/20 0.50
EHMT1 Q9H9B1 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.47
PDE7A Q13946 3/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 2/20 0.40
RECQL P46063 1/20 0.40
LMNA P02545 2/20 0.40
PLK4 O00444 1/20 0.39
HTT P42858 2/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11134251 0.85 EHMT2 (0.61) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL30548750 0.85 EHMT2 (0.61) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL28048983 0.79 HSD17B10 (0.46) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL301719 0.78 EHMT2 (0.70) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL10423274 0.78 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL31638084 0.76 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL1338872 0.76 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL4439023 0.76 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL11228968 0.76 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL10891052 0.75 EHMT2 (0.67) ALDH1A1MEN1KMT2AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1683804-B1 PLATINUM COMPLEX AND LUMINESCENT ELEMENT TAKASAGO PERFUMERY CO LTD (JP) 2013-07-31 EP disclosed
CN-102770415-A Polycyclic compounds as lysophosphatidic acid receptor antagonists AMIRA PHARMACEUTICALS INC 2012-11-07 CN disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
EP-1683804-A2 PLATINUM COMPLEX AND LUMINESCENT ELEMENT Takasago International Corporation (JP) 2006-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070103060-A1 Platinum complex and light emitting device UBE2D3, PCID2, CCND2 ALDH1A1 2944/4885MEN1 1473/4885KMT2A 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.