Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121549 | 0.83 | GRM6 (0.49) | KMT2AALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL924085 | 0.73 | ALDH1A1 (0.56) | KMT2AALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL614077 | 0.70 | ALDH1A1 (0.37) | KMT2AALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL5949858 | 0.69 | SLC6A4 (0.54) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL14267699 | 0.68 | KMT2A (0.69) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL7143736 | 0.67 | SLC6A4 (0.44) | KMT2AALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL306012 | 0.67 | MEN1 (0.46) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL29441715 | 0.67 | MEN1 (0.65) | KMT2AALDH1A1MEN1MAPTRAB9A | |
| SCHEMBL2878741 | 0.67 | MEN1 (0.65) | KMT2AALDH1A1MEN1MAPTRAB9A | |
| SCHEMBL29441683 | 0.66 | PLG (0.59) | KMT2AALDH1A1MEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004325-A1 | PTP1B inhibitors | WYETH (US) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004325-A1 | PTP1B inhibitors | PTPA, PTPRJ, PTPRR | KMT2A 2570/4885ALDH1A1 1266/4885SMN1; SMN2 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.