Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.77 |
| ▸ | DRD3 | P35462 | 13/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.77 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925392 | 0.93 | DRD2 (0.80) | DRD2DRD3ADRA1AHRH4SIGMAR1 | |
| SCHEMBL4930246 | 0.88 | DRD2 (0.82) | DRD2DRD3ADRA1AHRH4SIGMAR1 | |
| SCHEMBL14491418 | 0.88 | DRD2 (0.84) | DRD2DRD3ADRA1AHRH4SIGMAR1 | |
| SCHEMBL4924188 | 0.87 | DRD2 (0.86) | DRD2DRD3ADRA1AHRH4SIGMAR1 | |
| SCHEMBL4934368 | 0.87 | DRD2 (1.00) | DRD2DRD3ADRA1AHRH4SIGMAR1 | |
| SCHEMBL4928946 | 0.87 | DRD2 (0.89) | DRD2DRD3ADRA1AHRH4SIGMAR1 | |
| SCHEMBL4932903 | 0.86 | DRD2 (0.82) | DRD2DRD3ADRA1AHRH4SIGMAR1 | |
| SCHEMBL4932884 | 0.86 | DRD2 (0.84) | DRD2DRD3ADRA1AHRH4SIGMAR1 | |
| SCHEMBL5181059 | 0.86 | DRD2 (0.98) | DRD2DRD3ADRA1AHRH4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4932537 | 0.86 | DRD2 (0.98) | DRD2DRD3ADRA1AHRH4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432269-B2 | Arylpiperaszine derivatives, to the process for the production thereof and to the use thereof as therapeutic agents | BIOPROJET (FR) | 2008-10-07 | — | — | US | disclosed |