Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12267055 | 0.86 | L3MBTL1 (0.61) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL12267104 | 0.84 | L3MBTL1 (0.67) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL25384005 | 0.83 | L3MBTL1 (0.57) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL25383941 | 0.83 | L3MBTL1 (0.57) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL30509199 | 0.81 | HTT (0.57) | L3MBTL1S1PR1MAPTRAB9ANPC1 | |
| SCHEMBL428750 | 0.81 | HTT (0.57) | L3MBTL1S1PR1MAPTRAB9ANPC1 | |
| SCHEMBL7453298 | 0.81 | L3MBTL1 (0.54) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL12586374 | 0.81 | L3MBTL1 (0.62) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL15261955 | 0.80 | L3MBTL1 (0.56) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL25383050 | 0.80 | L3MBTL1 (0.57) | L3MBTL1S1PR1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968157-B2 | Discotic nematic material, composition, retardation plate, elliptically-polarizing plate and compound | FUJIFILM CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7968156-B2 | Compound, composition, retardation plate, elliptically-polarizing plate and liquid-crystal display device | FUJIFILM CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7944530-B2 | Optical film, polarizing plate and liquid crystal display device including an optically anisotropic layer formed from a mixture including two or more liquid crystal compounds | FUJIFILM CORPORATION (JP) | 2011-05-17 | — | — | US | disclosed |
| US-20090233009-A1 | COMPOUND, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090096961-A1 | OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-04-16 | — | — | US | disclosed |
| US-20090068378-A1 | DISCOTIC NEMATIC MATERIAL, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND COMPOUND | FUJIFILM CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
| US-7431972-B2 | Optical film, and polarizing plate and liquid crystal display device using the same | FUJIFILM CORPORATION (JP) | 2008-10-07 | — | — | US | disclosed |
| US-7425555-B2 | Heteroaryl substituted biphenyl derivatives as p38 kinase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-09-16 | — | — | US | disclosed |
| EP-1499600-B1 | HETEROARYL SUBSTITUTED BIPHENYL DERIVATIVES AS P38 KINASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-07-25 | — | — | EP | disclosed |
| US-20070065601-A1 | Optical film, and polarizing plate and liquid crystal display device using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |
| US-5801170-A | Heterocyclic biphenylylamides useful as 5HT1D antagonists | SMITHKLINE BEECHAM PLC (GB) | 1998-09-01 | — | — | US | disclosed |
| EP-0733048-A1 | HETEROCYCLIC BIPHENYLYLAMIDES USEFUL AS 5HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-09-25 | — | — | EP | disclosed |
| EP-0716656-A1 | AMIDE DERIVATIVES AS 5HT1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-19 | — | — | EP | disclosed |
| US-5510350-A | USEFUL IN TREATMENT OR PROPHYLAXIS OF DEPRESSION AND OTHER CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO GROUP LIMITED (GB) | 1996-04-23 | — | — | US | disclosed |
| WO-1995015954-A1 | HETEROCYCLIC BIPHENYLYLAMIDES USEFUL AS 5HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-06-15 | — | — | WO | disclosed |
| WO-1995006644-A1 | AMIDE DERIVATIVES AS 5HT1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-03-09 | — | — | WO | disclosed |
| US-5340810-A | Useful in the treatment and prophylaxis of depression and other disorders of the central nervous system | GLAXO GROUP LIMITED (GB) | 1994-08-23 | — | — | US | disclosed |
| EP-0533268-A1 | Benzanilide derivatives as 5-HT1D antagonists | GLAXO GROUP LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068378-A1 | DISCOTIC NEMATIC MATERIAL, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND COMPOUND | H1-2, H1-0, CCNL2 | L3MBTL1 927/4885S1PR1 2805/4885CA12 3622/4885 |
| US-20090233009-A1 | COMPOUND, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE | PYM1, CCNA1, CCND1 | L3MBTL1 607/4885S1PR1 3678/4885CA12 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.