Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120317 | 0.81 | NPC1 (0.47) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5118668 | 0.75 | ALDH1A1 (0.46) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5116843 | 0.73 | MAPT (0.52) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3288477 | 0.73 | MEN1 (0.65) | MAPTSMN1; SMN2ALDH1A1MAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL8172216 | 0.72 | MEN1 (0.64) | MAPTSMN1; SMN2ALDH1A1MAPK1MEN1 | |
| SCHEMBL2421954 | 0.70 | MAPT (0.60) | MAPTSMN1; SMN2ALDH1A1MAPK1GAA | |
| SCHEMBL17847051 | 0.70 | POLB (0.53) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5949858 | 0.69 | SLC6A4 (0.54) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5122274 | 0.68 | NPC1 (0.42) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5126999 | 0.68 | MEN1 (0.39) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004325-A1 | PTP1B inhibitors | WYETH (US) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004325-A1 | PTP1B inhibitors | PTPA, PTPRJ, PTPRR | MAPT 3063/4885RAB9A 1436/4885SMN1; SMN2 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.