Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5126405 | 0.93 | MET (0.77) | METKDR | |
| SCHEMBL1871330 | 0.93 | MET (0.64) | METKDRFLT3 | |
| SCHEMBL1886244 | 0.93 | MET (0.73) | METKDRFLT3 | |
| SCHEMBL12637269 | 0.93 | MET (0.68) | METKDRFLT3 | |
| SCHEMBL1876629 | 0.91 | MET (0.74) | METKDRFLT3 | |
| SCHEMBL1880336 | 0.90 | MET (0.67) | METKDRFLT3 | |
| SCHEMBL12637272 | 0.90 | MET (0.67) | METKDRFLT3 | |
| SCHEMBL1879546 | 0.90 | MET (0.78) | METKDRFLT3 | |
| SCHEMBL1879800 | 0.89 | MET (0.78) | METKDRFLT3 | |
| SCHEMBL1876730 | 0.89 | MET (0.73) | METKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425564-B2 | Quinoline derivative and quinazoline derivative inhibiting self-phosphorylation of hepatocytus prolifertor receptor and medicinal composition containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2008-09-16 | — | — | US | disclosed |