Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962499 | 1.00 | NPC1 (0.33) | NPC1CTSA | |
| SCHEMBL5109495 | 0.91 | NPC1 (0.33) | NPC1 | |
| SCHEMBL5109499 | 0.91 | NPC1 (0.33) | NPC1 | |
| SCHEMBL4963099 | 0.85 | NPC1 (0.34) | NPC1 | |
| SCHEMBL4965043 | 0.82 | CTSA (0.33) | CTSA | |
| SCHEMBL4962050 | 0.82 | CTSA (0.33) | CTSA | |
| SCHEMBL4962044 | 0.82 | CTSA (0.33) | CTSA | |
| SCHEMBL4664638 | 0.82 | F11 (0.37) | NPC1 | |
| SCHEMBL4664634 | 0.82 | NPC1 (0.36) | NPC1 | |
| SCHEMBL4664726 | 0.79 | KDM4E (0.34) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280855-A1 | Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles | NYCOMED GMBH (DE) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280855-A1 | Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles | CYP1B1, CYP1A1, CYP3A4 | NPC1 1421/4885CTSA 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.