Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.66 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.66 |
| ▸ | MET | P08581 | 10/20 | 0.64 |
| ▸ | KDR | P35968 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635551 | 0.86 | PDGFRA (0.78) | FLT3PDGFRAMETKDR | |
| SCHEMBL1882872 | 0.86 | MET (0.84) | PDGFRAMETKDR | |
| SCHEMBL1871469 | 0.86 | MET (0.71) | FLT3PDGFRAMETKDR | |
| SCHEMBL1883279 | 0.86 | PDGFRA (0.72) | FLT3PDGFRAMETKDR | |
| SCHEMBL1881965 | 0.86 | MET (0.68) | FLT3PDGFRAMETKDR | |
| SCHEMBL1874854 | 0.86 | MET (0.73) | PDGFRAMETKDR | |
| SCHEMBL1875732 | 0.85 | MET (0.70) | FLT3PDGFRAMETKDR | |
| SCHEMBL1879396 | 0.85 | MET (0.73) | FLT3PDGFRAMETKDR | |
| SCHEMBL12635553 | 0.85 | MET (0.72) | FLT3PDGFRAMETKDR | |
| SCHEMBL1879879 | 0.85 | MET (0.65) | FLT3PDGFRAMETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425564-B2 | Quinoline derivative and quinazoline derivative inhibiting self-phosphorylation of hepatocytus prolifertor receptor and medicinal composition containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2008-09-16 | — | — | US | claimed |