SCHEMBL5121744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5121748	1.00	TAS2R14 (0.51)	TAS2R14TSHRPSEN1PSEN2APH1B
	SCHEMBL5122055	0.90	KDM4E (0.53)	TAS2R14PSEN1PSEN2APH1BNCSTN
	SCHEMBL5122060	0.90	KDM4E (0.53)	TAS2R14PSEN1PSEN2APH1BNCSTN
	SCHEMBL5116620	0.89	TAS2R14 (0.64)	TAS2R14PSEN1PSEN2APH1BNCSTN
	SCHEMBL5116607	0.89	TAS2R14 (0.64)	TAS2R14PSEN1PSEN2APH1BNCSTN
	SCHEMBL5121062	0.88	MAPT (0.54)	TAS2R14BMP1KDM4EALDH1A1MAPT
	SCHEMBL5121059	0.88	MAPT (0.54)	TAS2R14BMP1KDM4EALDH1A1MAPT
	SCHEMBL5114629	0.87	PSEN1 (0.53)	TAS2R14PSEN1PSEN2APH1BNCSTN
	SCHEMBL5117419	0.87	MAPT (0.55)	TAS2R14PSEN1PSEN2APH1BNCSTN
	SCHEMBL5117413	0.87	MAPT (0.55)	TAS2R14PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.