Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.85 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.85 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.85 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.85 |
| ▸ | PDE5A | O76074 | 2/20 | 0.68 |
| ▸ | PDE1A | P54750 | 2/20 | 0.68 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.68 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.68 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.63 |
| ▸ | PI4KA | P42356 | 1/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.63 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.63 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.59 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5125772 | 0.86 | HTT (0.73) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL31088348 | 0.86 | HTT (0.68) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL1832682 | 0.85 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL17933852 | 0.84 | ADORA2A (0.74) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL11459985 | 0.82 | SMN1; SMN2 (0.64) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| Bw-A78U SCHEMBL1883213 | 0.81 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL27388300 | 0.81 | YTHDC1 (1.00) | YTHDC1ADORA2A | |
| SCHEMBL7644240 | 0.80 | HTT (0.68) | PDE4APDE4BPDE4CPDE4DHTT | |
| Bw-A78U SCHEMBL11014914 | 0.80 | PDE4A (0.97) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL29133991 | 0.79 | HPGD (0.80) | PDE4APDE4BPDE4CPDE4DHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280926-A1 | Phosphodiesterase Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280926-A1 | Phosphodiesterase Inhibitors | PDE4A, PDE4B, PDE4C | PDE4A 1/4885PDE4B 2/4885PDE4C 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.