Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058603 | 0.90 | HTR6 (0.53) | HTR6ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL4047803 | 0.90 | HTR6 (0.53) | HTR6ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL4047804 | 0.90 | HTR6 (0.42) | HTR6DRD4ALDH1A1MAPK1HTR2A | |
| SCHEMBL5785901 | 0.90 | HTR6 (0.53) | HTR6ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL4058499 | 0.90 | HTR6 (0.42) | HTR6DRD4ALDH1A1MAPK1HTR2A | |
| SCHEMBL14177905 | 0.90 | HTR6 (0.42) | HTR6DRD4ALDH1A1MAPK1HTR2A | |
| SCHEMBL14177904 | 0.89 | HTR6 (0.43) | HTR6DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL4050240 | 0.89 | HTR6 (0.43) | HTR6DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL4057234 | 0.89 | HTR6 (0.43) | HTR6DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL4053320 | 0.83 | HTR6 (0.46) | HTR6ADRA1DADRA1AADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388024-B2 | Indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-06-17 | — | — | US | claimed |