Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231989 | 0.97 | KDM4E (0.45) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5129239 | 0.92 | STING1 (0.46) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3355952 | 0.90 | TLR7 (0.48) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4309229 | 0.89 | STING1 (0.46) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5126615 | 0.89 | CYP3A4 (0.42) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5115537 | 0.86 | STING1 (0.42) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3353897 | 0.85 | TLR7 (0.47) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4156877 | 0.85 | KDM4E (0.44) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12888449 | 0.85 | KDM4E (0.44) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1232968 | 0.84 | TLR7 (0.45) | STING1DRD2DYRK1ABRD4STK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015184-A1 | Urea Substituted Imidazopyridines, Imidazoquinolines, and Imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-01-17 | — | — | US | disclosed |
| WO-2005123079-A2 | UREA SUBSTITUTED IMIDAZOPYRIDINES, IMIDAZOQUINOLINES, AND IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015184-A1 | Urea Substituted Imidazopyridines, Imidazoquinolines, and Imidazonaphthyridines | IL2, EIF2AK2, IL4 | STING1 25/4885CYP3A4 703/4885CYP2D6 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.