Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 16/20 | 0.90 |
| ▸ | MAPK12 | P53778 | 16/20 | 0.90 |
| ▸ | MAPK11 | Q15759 | 16/20 | 0.90 |
| ▸ | MAPK14 | Q16539 | 16/20 | 0.90 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | BCR | P11274 | 2/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114945 | 0.94 | MAPK14 (1.00) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5125496 | 0.94 | MAPK13 (0.88) | MAPK13MAPK12MAPK11MAPK14CYP1A2 | |
| SCHEMBL5125061 | 0.92 | MAPK13 (0.82) | MAPK13MAPK12MAPK11MAPK14CYP1A2 | |
| SCHEMBL5119305 | 0.84 | MAPK14 (0.90) | MAPK13MAPK12MAPK11MAPK14 | |
| Hydrochloric Acid SCHEMBL5126323 | 0.84 | MAPK14 (0.88) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5121209 | 0.79 | MAPK14 (0.86) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5126852 | 0.79 | MAPK13 (0.65) | MAPK13MAPK12MAPK11MAPK14DYRK1A | |
| SCHEMBL5119987 | 0.79 | MAPK14 (1.00) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5115462 | 0.79 | MAPK14 (0.85) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL14132080 | 0.78 | MAPK14 (0.84) | MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167314-A1 | Condensed Imidazole Compound And Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080167314-A1 | Condensed Imidazole Compound And Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080167314-A1 | Condensed Imidazole Compound And Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-10 | — | — | US | disclosed |
| EP-1832588-A1 | CONDENSED IMIDAZOLE COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-09-12 | — | — | EP | disclosed |
| EP-1832588-A1 | CONDENSED IMIDAZOLE COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167314-A1 | Condensed Imidazole Compound And Use Thereof | MAPK13, MMP13, MAPK3 | MAPK13 1/4885MAPK12 9/4885MAPK11 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.