Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120611 | 0.92 | PTGER1 (0.49) | MMP13NPC1MAPTRAB9AMMP1 | |
| SCHEMBL4723594 | 0.92 | PTGER1 (0.56) | MMP13NPC1MAPTRAB9AMMP1 | |
| SCHEMBL5130507 | 0.90 | MAPT (0.47) | MMP13NPC1MAPTRAB9AMMP1 | |
| SCHEMBL5128854 | 0.88 | MAPT (0.46) | MMP13NPC1MAPTRAB9AMMP1 | |
| SCHEMBL5125098 | 0.87 | MMP13 (0.54) | MMP13NPC1MAPTRAB9AMMP1 | |
| SCHEMBL5126971 | 0.87 | PTGER1 (0.62) | MMP13NPC1MAPTRAB9AMMP1 | |
| SCHEMBL5123534 | 0.87 | PTGER1 (0.61) | PTGER1MRGPRX4LRRK2SRPK3 | |
| SCHEMBL5125052 | 0.87 | MRGPRX4 (0.48) | MMP13NPC1MAPTRAB9AMMP1 | |
| SCHEMBL5120632 | 0.87 | MAPT (0.50) | MMP13NPC1MAPTRAB9AMMP1 | |
| SCHEMBL5117461 | 0.86 | MAPT (0.45) | MMP13NPC1MAPTRAB9AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207708-A1 | Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders | GLAXO GROUP LIMITED (GB) | 2008-08-28 | — | — | US | disclosed |
| US-20080207708-A1 | Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders | GLAXO GROUP LIMITED (GB) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207708-A1 | Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders | PTGER1, PTGER2, PTGER4 | MMP13 2521/4885NPC1 3020/4885MAPT 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.