Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 10/20 | 0.83 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.83 |
| ▸ | ITGAL | P20701 | 10/20 | 0.83 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.63 |
| ▸ | ACE | P12821 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5129578 | 1.00 | ITGB2 (0.83) | ITGB2ICAM1ITGALPOLBUSP2 | |
| SCHEMBL15145373 | 0.91 | ITGB2 (0.76) | ITGB2ICAM1ITGALPOLBUSP2 | |
| SCHEMBL8744722 | 0.86 | P2RY14 (0.68) | ITGB2ICAM1ITGALPOLBTP53 | |
| SCHEMBL8744719 | 0.86 | P2RY14 (0.68) | ITGB2ICAM1ITGALPOLBTP53 | |
| SCHEMBL15780958 | 0.84 | ITGB2 (0.79) | ITGB2ICAM1ITGALPOLBTP53 | |
| SCHEMBL11875059 | 0.84 | ERAP2 (0.72) | ITGB2ICAM1ITGALPOLBKDM4E | |
| SCHEMBL21623652 | 0.84 | ERAP2 (0.72) | ITGB2ICAM1ITGALPOLBKDM4E | |
| SCHEMBL15145392 | 0.84 | ITGB2 (0.72) | ITGB2ICAM1ITGALPOLBALDH1A1 | |
| SCHEMBL11864161 | 0.84 | ERAP2 (0.72) | ITGB2ICAM1ITGALPOLBKDM4E | |
| SCHEMBL15145401 | 0.84 | ITGB2 (0.79) | ITGB2ICAM1ITGALUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144728-A1 | CONJUGATES WHICH BIND A BLOOD PROTEIN SUCH AS HUMAN SERUM ALBUMIN AND METHODS OF USING THE SAME IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO IMAGING S.P.A. (IT) | 2008-11-27 | — | — | WO | disclosed |