SCHEMBL513073

SCHEMBL513073

C=C(C)C(=O)OCCC(O)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.45
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
MTNR1A P48039 2/20 0.40
MTNR1B P49286 2/20 0.40
ELANE P08246 1/20 0.40
THRB P10828 1/20 0.39
TSHR P16473 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
HPGD P15428 2/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17938235 0.88 TSHR (0.47) TDP1POLBAPEX1HTTMTNR1A
SCHEMBL29791076 0.86 PPARG (0.46) TDP1POLBAPEX1HTTELANE
SCHEMBL18388075 0.83 ELANE (0.43) TDP1POLBAPEX1HTTELANE
SCHEMBL3629782 0.83 HTT (0.41) TDP1POLBAPEX1HTTTHRB
SCHEMBL29381744 0.81 HPGD (0.52) TDP1POLBAPEX1HTTELANE
SCHEMBL93360 0.81 HPGD (0.52) TDP1POLBAPEX1HTTELANE
SCHEMBL235139 0.80 MTNR1A (0.49) TDP1POLBAPEX1HTTMTNR1A
SCHEMBL13559176 0.79 ELANE (0.47) TDP1POLBAPEX1HTTMTNR1A
SCHEMBL7184070 0.79 TDP1 (0.51) TDP1POLBAPEX1HTTMTNR1A
Formaldehyde SCHEMBL28047211 0.79 POLB (0.48) TDP1POLBAPEX1HTTMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210381-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS Alcon Universal, Ltd. (CH) 2002-06-05 EP claimed
WO-2001018079-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON UNIVERSAL LTD. (CH) 2001-03-15 WO claimed
US-9957343-B2 Ionic bonding group-containing comb polymers BYK-CHEMIE, GMBH (DE) 2018-05-01 US disclosed
US-9556299-B2 Surface-active comb copolymers BYK-CHEMIE GMBH (DE) 2017-01-31 US disclosed
US-20150203619-A1 SURFACE-ACTIVE COMB COPOLYMERS BYK-CHEMIE GMBH (DE) 2015-07-23 US disclosed
US-20150152211-A1 IONIC BONDING GROUP-CONTAINING COMB POLYMERS BYK-CHEMIE GMBH (DE) 2015-06-04 US disclosed
US-8398235-B2 Plastic lens for spectacles, process for producing the same, and coating liquid applicator for use in the process HOYA CORPORATION (JP) 2013-03-19 US disclosed
US-20130018121-A1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-CHEMIE GMBH (DE) 2013-01-17 US disclosed
US-20120029104-A1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-CHEMIE GMBH (DE) 2012-02-02 US disclosed
US-20100014048-A1 PLASTIC LENS FOR SPECTACLES, PROCESS FOR PRODUCING THE SAME, AND COATING LIQUID APPLICATOR FOR USE IN THE PROCESS HOYA CORPORATION (JP) 2010-01-21 US disclosed
EP-2093605-A1 PLASTIC LENS FOR SPECTACLES, PROCESS FOR PRODUCING THE SAME, AND COATING LIQUID APPLICATOR FOR USE IN THE PROCESS HOYA CORPORATION (JP) 2009-08-26 EP disclosed
EP-1210381-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS Alcon Universal, Ltd. (CH) 2002-06-05 EP disclosed
WO-2001018079-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON UNIVERSAL LTD. (CH) 2001-03-15 WO disclosed
EP-0360617-A2 Dry toner, dry developer and process for forming images Hitachi Chemical Co., Ltd. (JP) 1990-03-28 EP disclosed