SCHEMBL5131614

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6469026	0.89	DPP4 (0.53)	OPRK1OPRM1OPRD1BCHEDPP4
	SCHEMBL6471110	0.89	DPP4 (0.53)	OPRK1OPRM1OPRD1BCHEDPP4
	SCHEMBL6468987	0.87	MEN1 (0.53)	OPRK1OPRM1OPRD1BCHEATM
	SCHEMBL6470305	0.87	ATM (0.47)	OPRK1OPRM1OPRD1DPP4ATM
	SCHEMBL6471055	0.87	MAOB (0.47)	OPRK1OPRM1OPRD1DPP4KMT2A
	SCHEMBL5042774	0.86	TMEM97 (0.57)	OPRK1OPRM1OPRD1DPP4VNN1
	SCHEMBL6469199	0.86	DPP4 (0.49)	OPRK1OPRM1OPRD1DPP4ATM
	SCHEMBL5133518	0.85	DPP4 (0.44)	OPRK1OPRM1OPRD1DPP4VNN1
	SCHEMBL6468961	0.84	VNN1 (0.53)	OPRK1VNN1KMT2ASLC6A4ADRA1A
	SCHEMBL5132091	0.84	DPP4 (0.43)	OPRK1OPRM1OPRD1DPP4VNN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.