Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602058 | 0.86 | NPY2R (0.67) | NPY2RKMT2AMEN1MAPT | |
| SCHEMBL5081431 | 0.82 | NPY2R (0.67) | NPY2RALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL5084525 | 0.81 | NPY2R (0.74) | NPY2RALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL5080889 | 0.81 | NPY2R (0.66) | NPY2RALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL5080923 | 0.79 | NPY2R (0.74) | NPY2RALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7600687 | 0.79 | NPY2R (0.77) | NPY2RALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL14590786 | 0.79 | ALDH1A1 (0.69) | NPY2RALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL5083778 | 0.77 | NPY2R (0.71) | NPY2RALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL5079928 | 0.77 | NPY2R (1.00) | NPY2RALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL5084490 | 0.77 | NPY2R (0.74) | NPY2RALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183239-B2 | Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-22 | — | — | US | claimed |