Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5131755 | 0.77 | CYP2D6 (0.52) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL5080997 | 0.77 | FDPS (0.49) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL5084645 | 0.75 | FDPS (0.42) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL24804995 | 0.66 | FDPS (0.53) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL29515049 | 0.66 | FDPS (0.53) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL11666395 | 0.66 | FDPS (0.53) | FDPSCYP2D6MEN1LMNATP53 | |
| Trifluoroacetic Acid SCHEMBL30017784 | 0.66 | FDPS (0.38) | FDPSMEN1LMNATP53KMT2A | |
| SCHEMBL288736 | 0.64 | FDPS (0.52) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL644279 | 0.64 | FDPS (0.52) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL5782951 | 0.64 | FDPS (0.52) | FDPSCYP2D6MEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183239-B2 | Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-22 | — | — | US | claimed |