Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.65 |
| ▸ | CNR1 | P21554 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132524 | 0.82 | CNR2 (0.69) | CNR2CNR1KCNH2 | |
| SCHEMBL584425 | 0.81 | CNR2 (0.67) | CNR2CNR1KCNH2 | |
| SCHEMBL1609270 | 0.81 | CNR2 (0.69) | CNR2CNR1KCNH2 | |
| SCHEMBL584109 | 0.79 | CNR2 (1.00) | CNR2CNR1KCNH2 | |
| SCHEMBL583386 | 0.78 | CNR2 (1.00) | CNR2CNR1KCNH2 | |
| SCHEMBL585484 | 0.78 | CNR2 (0.84) | CNR2CNR1KCNH2 | |
| SCHEMBL5189054 | 0.78 | CNR2 (0.61) | CNR2CNR1KCNH2 | |
| SCHEMBL1608949 | 0.78 | CNR2 (0.63) | CNR2CNR1KCNH2 | |
| SCHEMBL584424 | 0.78 | CNR2 (0.88) | CNR2CNR1KCNH2 | |
| SCHEMBL1609630 | 0.77 | CNR2 (0.65) | CNR2CNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001856-A1 | CRYSTALLINE FORMS OF N- {2-TERT -BUTYL -1- [ (4,4- DIF LUOROCYCLOHEXYL) METHYL]-LH-BENZIMIDAZOL-5- YL}ETHANESULFONAMIDE SALTS | AstraZeneca AB (SE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007108754-A1 | CRYSTALLINE FORMS OF N- {2-TERT -BUTYL -1- [ (4,4- DIF LUOROCYCLOHEXYL) METHYL] -LH-BENZIMIDAZOL-5- YL}ETHANESULFONAMIDE SALTS | ASTRAZENECA AB (SE) | 2007-09-27 | — | — | WO | disclosed |