Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 19/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077949 | 0.80 | NPY2R (0.70) | NPY2R | |
| SCHEMBL5132874 | 0.79 | NPY2R (0.53) | NPY2R | |
| SCHEMBL5132872 | 0.79 | NPY2R (0.53) | NPY2R | |
| SCHEMBL5132871 | 0.78 | NPY2R (0.43) | NPY2RADORA2AADORA1 | |
| SCHEMBL5132900 | 0.72 | NPY2R (0.63) | NPY2R | |
| SCHEMBL5128110 | 0.71 | NPY2R (0.67) | NPY2R | |
| SCHEMBL5077991 | 0.69 | NPY2R (0.73) | NPY2R | |
| SCHEMBL7607333 | 0.67 | NPY2R (0.68) | NPY2R | |
| SCHEMBL7599325 | 0.66 | NPY2R (0.67) | NPY2R | |
| SCHEMBL5084478 | 0.63 | NPY2R (0.80) | NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183239-B2 | Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-22 | — | — | US | claimed |