SCHEMBL5132895

SCHEMBL5132895

CCC(CC)C(=O)Nc1ccc(N2CCN(C(CC)(CC)C(C(N)=O)c3ccc(F)c(F)c3)CC2)c(F)c1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPY2R P49146 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5128104 0.89 NPY2R (0.63) NPY2R
SCHEMBL5079893 0.76 NPY2R (1.00) NPY2R
SCHEMBL5132900 0.75 NPY2R (0.63) NPY2R
SCHEMBL5132899 0.75 NPY2R (0.75) NPY2R
SCHEMBL6115312 0.75 NPY2R (0.75) NPY2R
SCHEMBL4009548 0.74 NPY2R (0.61) NPY2R
Hydrochloric Acid SCHEMBL5077975 0.73 NPY2R (0.60) NPY2R
Hydrochloric Acid SCHEMBL4003406 0.73 NPY2R (0.60) NPY2R
SCHEMBL4004710 0.73 NPY2R (0.60) NPY2R
SCHEMBL3660397 0.73 NPY2R (0.84) NPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183239-B2 Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor JANSSEN PHARMACEUTICA NV (BE) 2012-05-22 US claimed