Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 2/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4099431 | 1.00 | HRH3 (0.34) | HRH3XIAPBIRC2CES2CES1 | |
| SCHEMBL4097155 | 1.00 | HRH3 (0.34) | HRH3XIAPBIRC2CES2CES1 | |
| SCHEMBL13723139 | 1.00 | HRH3 (0.34) | HRH3XIAPBIRC2CES2CES1 | |
| SCHEMBL4102926 | 0.81 | HRH3 (0.35) | HRH3XIAPBIRC2 | |
| SCHEMBL4094000 | 0.81 | HRH3 (0.35) | HRH3XIAPBIRC2 | |
| SCHEMBL5133764 | 0.81 | HRH3 (0.35) | HRH3XIAPBIRC2 | |
| SCHEMBL14035277 | 0.81 | CHRM2 (0.35) | CES2CES1 | |
| SCHEMBL14035268 | 0.81 | CHRM2 (0.35) | CES2CES1 | |
| SCHEMBL14035485 | 0.81 | CHRM2 (0.35) | CES2CES1 | |
| SCHEMBL4107027 | 0.80 | HRH3 (0.38) | HRH3XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134036-A1 | ALPHA-SUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-α]PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |