Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133476 | 0.91 | HPGD (0.50) | MAOBMEN1KMT2AHPGDPOLB | |
| SCHEMBL5132492 | 0.79 | KDR (0.55) | TSHR | |
| Hydrochloric Acid SCHEMBL27720720 | 0.78 | TERT (0.39) | TERTMAOBCYP1A2TSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL3040466 | 0.78 | KDR (0.42) | TERTMAOBCYP1A2TSHRNFKB1 | |
| SCHEMBL14559496 | 0.74 | KDR (0.62) | TERTPARP1 | |
| SCHEMBL5551798 | 0.74 | KDR (0.62) | TERTPARP1 | |
| Hydrochloric Acid SCHEMBL3045167 | 0.73 | PARP1 (0.41) | TERTPARP1 | |
| Hydrochloric Acid SCHEMBL27720763 | 0.73 | PARP1 (0.40) | PARP1ITGB3ITGA2B | |
| SCHEMBL5043948 | 0.72 | FFAR1 (0.40) | CYP1A2FFAR1 | |
| SCHEMBL5134533 | 0.72 | FFAR1 (0.43) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |