Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047240 | 0.87 | CCNB2 (0.40) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL3038178 | 0.76 | GSK3B (0.41) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL8791684 | 0.71 | TP53 (0.60) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL19418900 | 0.70 | CHRM2 (0.48) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL3048043 | 0.69 | CCNB2 (0.35) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL5046874 | 0.69 | CCNB2 (0.41) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL2241939 | 0.69 | PTGS1 (0.49) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL13696680 | 0.68 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL30022454 | 0.68 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL16156565 | 0.67 | CHRM2 (0.48) | CHRM2CHRM4CHRM1CHRM3GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |