Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 3/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1546798 | 0.80 | ALDH1A1 (0.47) | GRIN1GRIN2BALDH1A1GAAKMT2A | |
| SCHEMBL1948128 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GAAKMT2AKDM4EPOLB | |
| SCHEMBL1546096 | 0.75 | MAPT (0.49) | ALDH1A1GAAKMT2AKDM4EMAPT | |
| SCHEMBL27800402 | 0.74 | GRIN1 (0.41) | GRIN1GRIN2BKMT2APOLBMAPT | |
| SCHEMBL1945200 | 0.72 | TSHR (0.54) | ALDH1A1GAAKMT2AKDM4EPOLB | |
| SCHEMBL1027780 | 0.72 | ALDH1A1 (0.50) | GRIN1GRIN2BALDH1A1PER2CRY2 | |
| SCHEMBL1945396 | 0.72 | TSHR (0.36) | ALDH1A1GAAKMT2AKDM4EMAPT | |
| SCHEMBL27617420 | 0.71 | KMT2A (0.37) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL11705032 | 0.71 | GRIN1 (0.40) | GRIN1GRIN2BPER2CRY2 | |
| SCHEMBL1944581 | 0.71 | TSHR (0.49) | ALDH1A1GAAKMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569994-B1 | MONOSUBSTITUTED 6-AMINOURACILS FOR THE STABILISATION OF HALOGENATED POLYMERS | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2008-01-09 | — | — | EP | disclosed |
| US-20060148941-A1 | Monosubstituted 6-aminouracils for the stabilization of halogenated polymers | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2006-07-06 | — | — | US | disclosed |
| CN-1720287-A | Monosubstituted 6-aminouracils for the stabilisation of halogenated polymers | CROMPTON VINYL ADDITIVES GMBH (DE) | 2006-01-11 | — | — | CN | disclosed |
| EP-1426406-A1 | Monosubstituted 6-aminouracils for stabilizing halogenated polymers | Crompton Vinyl Additives GmbH (DE) | 2004-06-09 | — | — | EP | disclosed |