Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3048852 | 0.88 | HRH3 (0.32) | HRH3ACHENR1H2 | |
| SCHEMBL3048856 | 0.88 | HRH3 (0.32) | HRH3ACHENR1H2 | |
| SCHEMBL27720805 | 0.87 | HRH3 (0.31) | HRH3ACHENR1H2 | |
| SCHEMBL5140104 | 0.85 | NR1H2 (0.34) | HRH3NR1H2ATRATRIP | |
| SCHEMBL3042343 | 0.77 | HRH3 (0.42) | HRH3ACHE | |
| SCHEMBL27700295 | 0.77 | HRH3 (0.42) | HRH3ACHE | |
| SCHEMBL3044021 | 0.76 | HRH3 (0.41) | HRH3ACHEAURKA | |
| SCHEMBL28772335 | 0.75 | HRH3 (0.41) | HRH3ACHE | |
| SCHEMBL28943660 | 0.75 | HRH3 (0.38) | HRH3ACHEATRATRIP | |
| SCHEMBL3159224 | 0.74 | HRH3 (0.39) | HRH3ATRATRIPAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |