Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,1-Dichloroethene SCHEMBL77385 | 0.97 | HSD17B10 (0.38) | HSD17B10TDP1ALDH1A1TSHRTP53 | |
| 1,1-Dichloroethene SCHEMBL10904360 | 0.95 | HSD17B10 (0.36) | HSD17B10TDP1ALDH1A1TSHRTP53 | |
| 1,1-Dichloroethene SCHEMBL28222101 | 0.95 | HSD17B10 (0.36) | HSD17B10TDP1ALDH1A1TSHRTP53 | |
| 1,1-Dichloroethene SCHEMBL28084136 | 0.95 | HSD17B10 (0.36) | HSD17B10TDP1ALDH1A1TSHRTP53 | |
| 1,1-Dichloroethene SCHEMBL379792 | 0.93 | HSD17B10 (0.35) | HSD17B10TDP1ALDH1A1 | |
| 1,1-Dichloroethene SCHEMBL28268717 | 0.93 | HSD17B10 (0.35) | HSD17B10TDP1ALDH1A1 | |
| Ethylene SCHEMBL6535677 | 0.90 | TDP1 (0.39) | HSD17B10TDP1ALDH1A1TSHRTP53 | |
| SCHEMBL28150973 | 0.90 | ALDH1A1 (0.38) | HSD17B10TDP1ALDH1A1TSHR | |
| Ethylene SCHEMBL994924 | 0.89 | ALDH1A1 (0.42) | HSD17B10TDP1ALDH1A1TSHRTP53 | |
| Ethylene SCHEMBL10561806 | 0.89 | ALDH1A1 (0.42) | HSD17B10TDP1ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793255-A | Heterocyclic compounds and their use | 无限药品股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| US-7435795-B2 | Stabilized hemoglobin solutions | NORTHFIELD LABORATORIES, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-20070173435-A1 | Stabilized hemoglobin solutions | NORTHFIELD LABORATORIES, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-7202341-B2 | Hemoglobin solution packaged in an oxygen and water vapor impermeable flexible container with a multi-layer film having at least a product contact layer, an oxygen and moisture barrier layer and an exterior layer for storage and preservation of deoxygenated hemoglobin solution | NORTHFIELD LABORATORIES, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-20060014671-A1 | Stabilized hemoglobin solutions | NORTHFIELD LABORATORIES, INC. (US) | 2006-01-19 | — | — | US | disclosed |
| EP-1381274-A1 | FLEXIBLE CONTAINER SYSTEM FOR STORAGE OF STABILIZED HEMOGLOBIN SOLUTIONS | Northfield Laboratories (US) | 2004-01-21 | — | — | EP | disclosed |
| US-20030065149-A1 | Stabilized hemoglobin solutions | NORTHFIELD LABORATORIES | 2003-04-03 | — | — | US | disclosed |
| WO-2002085111-A1 | FLEXIBLE CONTAINER SYSTEM FOR STORAGE OF STABILIZED HEMOGLOBIN SOLUTIONS | NORTHFIELD LABORATORIES (US) | 2002-10-31 | — | — | WO | disclosed |