Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | CALML3 | P27482 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SDHA | P31040 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826812 | 0.89 | MAOA (0.45) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3832498 | 0.84 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3829486 | 0.84 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3830901 | 0.83 | MAOA (0.42) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3826575 | 0.82 | MAOA (0.47) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL13607088 | 0.82 | MAOA (0.47) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3833142 | 0.78 | F10 (0.44) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3827610 | 0.78 | F10 (0.44) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3832503 | 0.77 | MAOA (0.42) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3830900 | 0.76 | MAOA (0.41) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987025-A1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pfizer Products Incorporated (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093904-A1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-23 | — | — | WO | disclosed |