Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316949 | 0.86 | ACHE (0.57) | ACHEEPHX1BCHE | |
| SCHEMBL24470495 | 0.81 | ACHE (0.61) | ACHEEPHX1BCHE | |
| Carbamic Acid SCHEMBL27650019 | 0.79 | EPHX1 (0.70) | ACHEEPHX1ALOX15BCHE | |
| SCHEMBL593415 | 0.78 | ACHE (0.76) | ACHEEPHX1ALOX15 | |
| SCHEMBL7284973 | 0.78 | — | — | |
| SCHEMBL514302 | 0.78 | — | — | |
| SCHEMBL31379789 | 0.78 | ACHE (0.68) | ACHEEPHX1 | |
| SCHEMBL31299255 | 0.78 | ACHE (0.68) | ACHEEPHX1ALOX15 | |
| Carbamic Acid SCHEMBL10537640 | 0.77 | ACHE (0.61) | ACHEEPHX1ALOX15 | |
| SCHEMBL42439 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080177038-A1 | Non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, therapeutic, diagnostic, and other biotechnology uses | AMBRX, INC (US) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177038-A1 | Non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, therapeutic, diagnostic, and other biotechnology uses | DNPEP, DAO, PTMS | ACHE 2830/4885EPHX1 4567/4885ALOX15 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.