SCHEMBL5134309

SCHEMBL5134309

CC(OCCN(C)C)OC(=O)C=CC(=O)OC(C)OCCN(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.38
CHRM4 P08173 3/20 0.38
CHRM5 P08912 3/20 0.38
CHRM1 P11229 3/20 0.38
CHRM3 P20309 3/20 0.38
CHRNA4 P43681 2/20 0.38
HCAR2 Q8TDS4 2/20 0.38
CHRNB2 P17787 1/20 0.38
KDM4E B2RXH2 6/20 0.36
ALDH1A1 P00352 2/20 0.36
HRH1 P35367 4/20 0.35
CYP2D6 P10635 4/20 0.35
ADRA2A P08913 3/20 0.35
ADRA2B P18089 3/20 0.35
HTR2C P28335 3/20 0.35
ADRA1A P35348 3/20 0.35
DRD3 P35462 3/20 0.35
CYP1A2 P05177 2/20 0.35
OPRK1 P41145 2/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016141 0.86 TSHR (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL3894850 0.79 CHRM1 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11215777 0.79 HCAR2 (0.42) HCAR2TSHR
SCHEMBL17871682 0.79 HCAR2 (0.44) HCAR2LMNATDP1TSHR
SCHEMBL11215771 0.79 HCAR2 (0.42) HCAR2TSHR
SCHEMBL5342251 0.79 HCAR2 (0.44) HCAR2LMNATDP1TSHR
SCHEMBL3517017 0.76 HCAR2 (0.50) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL2898516 0.76 ATM (0.53) HCAR2ALDH1A1LMNATSHR
SCHEMBL8416366 0.76 ATM (0.53) HCAR2ALDH1A1LMNATSHR
SCHEMBL2890705 0.76 ATM (0.53) HCAR2ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1735267-B1 AMINOALKYL SUBSTITUTED ESTERS AND AMIDES OF FUMARIC ACID FOR NEUTRALISING MALODOR GIVAUDAN SA (CH) 2008-07-23 EP disclosed